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Both competitive and non-competitive antagonists of N-methyl-D-aspartic acid disrupt brightness discrimination in rats

✍ Scribed by Andrew H. Tang; Philip M. Ho


Book ID
115881907
Publisher
Elsevier Science
Year
1988
Tongue
English
Weight
256 KB
Volume
151
Category
Article
ISSN
0014-2999

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Non-competitive antagonists of N-methyl-
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Primary cultures of embryonic rat cerebral cortex were treated after 17 days in vitro for 10 min with a single dose of the non-competitive antagonists of Nmethyl-D-aspartate (NMDA) receptor MK 801, TCP, and GK 11. They were then maintained in vitro for 31, 59, or 73 days, and then processed for the