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Ketobemidone, methadone and pethidine are non-competitive N-methyl-d-aspartate (NMDA) antagonists in the rat cortex and spinal cord

✍ Scribed by Bjarke Ebert; Steen Andersen; Povl Krogsgaard-Larsen


Book ID
118052854
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
389 KB
Volume
187
Category
Article
ISSN
0304-3940

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Primary cultures of embryonic rat cerebral cortex were treated after 17 days in vitro for 10 min with a single dose of the non-competitive antagonists of Nmethyl-D-aspartate (NMDA) receptor MK 801, TCP, and GK 11. They were then maintained in vitro for 31, 59, or 73 days, and then processed for the