Bosentan for digital ulcers in patients with systemic sclerosis
β Scribed by Yayoi NAGAI; Michiko HASEGAWA; Tomoyasu HATTORI; Etsuko OKADA; Osamu TAGO; Osamu ISHIKAWA
- Book ID
- 108578177
- Publisher
- John Wiley and Sons
- Year
- 2011
- Tongue
- French
- Weight
- 278 KB
- Volume
- 39
- Category
- Article
- ISSN
- 0385-2407
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π SIMILAR VOLUMES
## Abstract ## Objective Recurrent digital ulcers are a manifestation of vascular disease in patients with systemic sclerosis (SSc; scleroderma) and lead to pain, impaired function, and tissue loss. We investigated whether treatment with the endothelin receptor antagonist, bosentan, decreased the
Seibold and Jageneau state that "digital ulcerations in systemic sclerosis have been shown to respond equally to intraarterial reserpine and saline . . . yet recent textbooks of rheumatology continue to advocate use of this agent" (Sei-