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Successful treatment of systemic sclerosis-related digital ulcers and sarcoidosis with endothelin receptor antagonist (bosentan) therapy

✍ Scribed by J. Tillon; F. Hervé; D. Chevallier; J-F. Muir; H. Levesque; I. Marie


Book ID
108668751
Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
560 KB
Volume
154
Category
Article
ISSN
0007-0963

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## Abstract ## Objective Recurrent digital ulcers are a manifestation of vascular disease in patients with systemic sclerosis (SSc; scleroderma) and lead to pain, impaired function, and tissue loss. We investigated whether treatment with the endothelin receptor antagonist, bosentan, decreased the

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