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Boron-containing thiouracil derivatives for neutron-capture therapy of melanoma

✍ Scribed by Tjarks, Werner; Gabel, Detlef


Book ID
118178544
Publisher
American Chemical Society
Year
1991
Tongue
English
Weight
717 KB
Volume
34
Category
Article
ISSN
0022-2623

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Synthesis of boronated phenanthridinium
✍ Hadi Ghaneolhosseini; Werner Tjarks; Stefan SjΓΆberg πŸ“‚ Article πŸ“… 1997 πŸ› Elsevier Science 🌐 French βš– 406 KB

3, -p-carborane-l-yl)propyl]-6-phenyl phenanthridinium chloride hydrochloride (13) has been synthesised by reacting 3,8-diacetamido-6-phenylphenanthridine ) in nitrobenzene at 120Β°C for 4 days and subsequent removal of the protective groups using 33% HBr/AcOH. Conversion to the chloride hydrochlori