## Abstract Lipopolysaccharide (LPS) is a major mediator of inflammatory response. Periodontopathic bacterium __Porphyromonas gingivalis__ LPS has quite different character from __Escherichia coli__ LPS. __E. coli__ LPS is agonist for Tollβlike receptor 4 (TLR4), whereas __P. gingivalis__ LPS worke
Bone sialoprotein and its transcriptional regulatory mechanism
β Scribed by Y. Ogata
- Book ID
- 111262037
- Publisher
- John Wiley and Sons
- Year
- 2008
- Tongue
- English
- Weight
- 480 KB
- Volume
- 43
- Category
- Article
- ISSN
- 0022-3484
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## Abstract This study identifies a __cis__βacting element that confers tissueβrestricted expression to the bone sialoprotein (__BSP__) gene. Using both gain of function and lossβof function studies, we demonstrate that this element acts as a tissue specific enhancer of BSP expression in osteoblast
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