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Bone matrix mineralization in osteogenesis imperfecta type VI

✍ Scribed by N. Fratzl-Zelman; P. Roschger; I. Schmidt; F. Glorieux; K. Klaushofer; P. Fratzl; W. Wagermaier; F. Rauch

Book ID
119204245
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
54 KB
Volume
51
Category
Article
ISSN
8756-3282

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## Abstract Osteogenesis imperfecta (OI) is a spectrum of genetic disorders characterized by bone fragility. It is caused by dominant mutations affecting the synthesis and/or structure of type I procollagen or by recessively inherited mutations in genes responsible for the posttranslational process