Bone marrow-originated endothelial progenitor cells contribute to neovasculature of tumor
✍ Scribed by Yizhou Luo; Xi Wang; Ziheng Guo; Guanzheng Yu; Jiejun Wang
- Book ID
- 106314776
- Publisher
- Springer
- Year
- 2008
- Tongue
- English
- Weight
- 189 KB
- Volume
- 7
- Category
- Article
- ISSN
- 1610-1979
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## Abstract Despite extensive research, the contribution of bone‐marrow‐derived endothelial progenitor cells (BM‐EPC) to tumor angiogenesis remains controversial. In previous publications, the extent of incorporation of BM‐EPCs into the endothelial cell (EC) layer in different tumor models has been
## Abstract This study reports the culture and purification of murine bone marrow endothelial progenitor cells (EPCs) using endothelial cell‐conditioned medium (EC‐CM). Endothelial‐like cells appeared at day 5 in culture of bone marrow mononuclear cells in the presence of EC‐CM in the culture syste