Bone marrow and peripheral blood lym-phocytosis in the prognosis of chronic lymphocytic leukemia
β Scribed by Dr. Jan L. Gray; Alexander Jacobs; Matthew Block
- Publisher
- John Wiley and Sons
- Year
- 1974
- Tongue
- English
- Weight
- 728 KB
- Volume
- 33
- Category
- Article
- ISSN
- 0008-543X
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## Abstract ## BACKGROUND Patients with chronic lymphocytic leukemia (CLL) that transforms to Richter syndrome (RS) frequently show atypical lymphocytes in bone marrow; however, a diagnosis of RS requires confirmation of the presence of sheets of large cells in bone marrow or lymph nodes. ## METH
Although bone marrow biopsy pattern (BMBP) has long been suggested to be an independent prognostic factor in chronic lymphocytic leukemia (CLL), conflicting reports continue to appear in the literature. To investigate this issue we retrospectively reviewed 70 CLL patients who had undergone bone marr
The prognostic information of blood lymphocyte characteristics and clinical findings was assessed in 62 patients with chronic lymphocytic leukemia of B cell type. Bivariate and multivariate survival analyses were performed using age, Rai stage, surface membrane immunoglobulin (smIg,) isotype pattern