Bone loss in primary biliary cirrhosis: absence of association with severity of liver disease
✍ Scribed by Laurence Le Gars; Caroline Grandpierre; Olivier Chazouillères; Francis Berenbaum; Raoul Poupon
- Book ID
- 114371181
- Publisher
- Elsevier Science
- Year
- 2002
- Tongue
- English
- Weight
- 119 KB
- Volume
- 69
- Category
- Article
- ISSN
- 1297-319X
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📜 SIMILAR VOLUMES
Atraumatic fractures caused by osteoporosis may be a serious complication of primary biliary cirrhosis. Mean (&S.D.) bone mineral density in the lumbar spine in 210 ambulatory women with primary biliary cirrhosis was 1.02 +: 0.19 gm/cm2, 7% lower than that in 139 age-matched normal women (after adju
Keratins (K) 8 and 18 variants predispose carriers to the development of end-stage liver disease and patients with chronic hepatitis C to disease progression. Hepatocytes express K8/K18, whereas biliary epithelia express K8/K18/K19. K8-null mice, which are predisposed to liver injury, spontaneously