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Bone biomechanical properties in LRP5 mutant mice

✍ Scribed by M.P. Akhter; D.J. Wells; S.J. Short; D.M. Cullen; M.L. Johnson; G.R. Haynatzki; P. Babij; K.M. Allen; P.J. Yaworsky; F. Bex; R.R. Recker


Book ID
116318897
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
253 KB
Volume
35
Category
Article
ISSN
8756-3282

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Lrp5/6 co-receptor is known to play a role in bone formation and lipid metabolism. This gene encodes a member of the low-density lipoprotein (LDL) receptor gene family. This study tests the hypothesis that Lrp5/6 is necessary for the development of valve calcification in experimental hypercholestero