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Bone as a source of FGF23: regulation by phosphate?

✍ Scribed by Michiko Mirams; Bruce G. Robinson; Rebecca S. Mason; Anne E. Nelson

Book ID
116319005
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
433 KB
Volume
35
Category
Article
ISSN
8756-3282

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## Abstract The functional interaction between fibroblast growth factor 23 (FGF‐23) and Klotho in the control of vitamin D and phosphate homeostasis is manifested by the largely overlapping phenotypes of __Fgf23‐__ and __Klotho‐__deficient mouse models. However, to date, targeted inactivation of FG