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Bone apposition to titanium implants biocoated with recombinant human bone morphogenetic protein-2 (rhBMP-2). A pilot study in dogs

✍ Scribed by Jürgen Becker; Axel Kirsch; Frank Schwarz; Maria Chatzinikolaidou; Daniel Rothamel; Vojislav Lekovic; Herbert Peter Jennissen

Publisher: Springer
Year: 2006
Tongue: English
Weight: 445 KB
Volume: 10
Category: Article
ISSN: 1432-6981
DOI: 10.1007/s00784-006-0049-0

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Porous 50:50 poly(d,l lactide-co-glycolide) microspheres containing varying amounts of ''free'' recombinant human bone morphogenetic protein-2 (rhBMP-2) were evaluated for their ability to induce/enhance expression of osteoblastic characteristics by pluripotent mesenchymal cells in vitro. ''Free'' p