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Bombesin Promotes Synergistic Stimulation of DNA Synthesis by Ethanol and Insulin in Fibroblasts

โœ Scribed by Jagat J. Mukherjee; Jin-Sheng Huang; Crescent Getman; Zoltan Kiss


Book ID
115567449
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
124 KB
Volume
362
Category
Article
ISSN
0003-9861

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## Abstract Earlier work showed that thrombin stimulates proliferation of human fibroblasts in serumfree medium. This work demonstrates (1) that thrombin has to be present during most or all of the G1 period to ensure maximal DNA synthesis, (2) that DNA synthesis increases about three hours later a