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Blood–brain distribution of morphine-6-glucuronide in sheep

✍ Scribed by H H Villesen; D J R Foster; R N Upton; L L Christrup; A A Somogyi; A Martinez; C Grant


Book ID
110009304
Publisher
Nature Publishing Group
Year
2006
Tongue
English
Weight
138 KB
Volume
149
Category
Article
ISSN
0007-1188

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NASAL ADMINISTRATION OF MORPHINE-6-GLUCU
✍ L. Illum; S. S. Davis; M. Pawula; A. N. Fisher; D. A. Barrett; N. F. Farraj; P. 📂 Article 📅 1996 🏛 John Wiley and Sons 🌐 English ⚖ 412 KB 👁 2 views

The pharmacokinetics of morphine-6-glucuronide (M6G) after both intravenous dosing and nasal administration were studied in sheep. The nasal formulation consisted of M6G in combination with an absorption promoting delivery system in the form of chitosan. The mean half-life of M6G after intravenous a