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Blood–Brain Barrier Controls Carnitine Level in the Brain: A Study on a Model System with RBE4 Cells

✍ Scribed by Joanna E. Mroczkowska; Françoise S. Roux; Maciej J. Nałęcz; Katarzyna A. Nałęcz

Book ID
115585016
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
69 KB
Volume
267
Category
Article
ISSN
0006-291X

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Transport of carnitine in RBE4 cells - a
Transport of carnitine in RBE4 cells - an in vitro model of blood-brain barrier
✍ Joanna E. Mroczkowska; Françoise S. Roux; Hans-Joachim Galla; Maciej J. Nalecz; 📂 Article 📅 1996 🏛 John Wiley and Sons 🌐 English ⚖ 514 KB

Accumulation of carnitine was studied in immortalized rat brain capillary endothelial cells R B E ~, as an in vitro model of blood-brain barrier. Both uptake and efflux phenomena were found independent on "a+] gradient. A quick acylation of carnitine in RBE4 cells was observed, especially leading to