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Blood sampling regimens for determination of methadone clearance

✍ Scribed by Cousins, M.J.; Plummer, J.L.; Gourlay, G.K.; Cherry, D.A.


Book ID
122363057
Publisher
Elsevier Science
Year
1987
Tongue
English
Weight
95 KB
Volume
30
Category
Article
ISSN
0304-3959

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A stereoselective analysis of methadone (Mtd) in whole blood and serum was developed using liquid chromatography on a protein based chiral stationary phase. Liquid-liquid extraction (LLE) and solid phase extraction methods were applied before chromatographic analysis. The extraction procedure, as we