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Blood-brain barrier disruption in the hypothalamus of young adult spontaneously hypertensive rats

✍ Scribed by Masaki Ueno; Haruhiko Sakamoto; Ying-Jun Liao; Masayuki Onodera; Cheng-Long Huang; Hiroshi Miyanaka; Toshitaka Nakagawa


Publisher
Springer
Year
2004
Tongue
English
Weight
540 KB
Volume
122
Category
Article
ISSN
1432-119X

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## Abstract Dextran‐magnetite particles (DMP) were studied for their use as a MR contrast agent to visualize lesions with a blood‐brain barrier (bbb) disruption. A freezing injury to the rat cerebral cortex was used as a model of bbb disruption. The biodistribution of iv‐injected DMP was studied us