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Blood-brain barrier characteristic enzymatic properties in cultured brain capillary endothelial cells

✍ Scribed by Jörg Meyer; Uwe Mischeck; Maike Veyhl; Karin Henzel; Hans-Joachim Galla


Book ID
115801095
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
464 KB
Volume
514
Category
Article
ISSN
0006-8993

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## Abstract Claudins are thought to be major components of tight junctions (TJs), and claudin‐5 and ‐12 are localized at TJs of the blood‐brain barrier (BBB). Claudin‐5‐deficient mice exhibit size‐selective (<800 Da) opening of the BBB. The purpose of this study was to clarify the expression levels