A new astrocytic cell line which is able to induce a blood-brain barrier property in cultured brain capillary endothelial cells
β Scribed by Carsten T. Beuckmann; Katja Dernbach; Ansgar Hakvoort; Hans-Joachim Galla
- Book ID
- 110256461
- Publisher
- Springer
- Year
- 1997
- Tongue
- English
- Weight
- 432 KB
- Volume
- 24
- Category
- Article
- ISSN
- 0920-9069
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π SIMILAR VOLUMES
Vascular endothelial cells (EC) exhibit organ-to-organ heterogeneity in their functions and morphologies. In particular, brain capillary EC have unique characteristics exemplified by the blood-brain barrier (BBB). The formation and the maintenance of BBB have been ascribed to EC responses to inducti
## Abstract The breakdown of the bloodβbrain barrier (BBB) has been considered to be a key step in the disease process of a number of neurological disorders such as cerebral ischemia and Alzheimer's disease. Many in vitro BBB models derived from animal tissues have been established to elucidate the