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Blood-brain barrier active efflux transporters: ATP-binding cassette gene family

✍ Scribed by Löscher, Wolfgang ;Potschka, Heidrun


Book ID
119923122
Publisher
American Society for Experimental NeuroTherapeutics
Year
2005
Tongue
English
Weight
166 KB
Volume
2
Category
Article
ISSN
1545-5343

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Active drug efflux transporters of the ATP binding cassette (ABC)-containing family of proteins have a major impact on the pharmacological behavior of most of the drugs in use today. Pharmacological properties affected by ABC transporters include the oral bioavailability, hepatobiliary, direct intes