Blood and tissue distribution of cyclosporin A after a single oral dose in the rat
β Scribed by K. Nooter; B. Meershoek; W. Spaans; P. Sonneveld; R. Oestrum; J. Deurloo
- Publisher
- Springer
- Year
- 1984
- Tongue
- English
- Weight
- 345 KB
- Volume
- 40
- Category
- Article
- ISSN
- 1420-682X
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract The metabolism of tetraphenyltin in rat liver and kidney has been examined. Tetraphenyltin and its metabolites in the tissue were determined periodically for 96 h after a single oral dose of 55.4 mg kg^β1^ of tetraphenyltin by gas chromatography. The gas chromatographic method was able
## Abstract Circadian variations in the pharmacokinetics, tissue distribution and urinary excretion of nifedipine were examined in fasted rats after administering a single oral dose at three different dosing times (08:00 am, 16:00 pm, 00:00 am). The plasma concentrations, the areas under the plasma
The distribution of 2-t-butyl-4-methoxyphenol (BHA) and its conversion to 2,2'-dihydroxy-3,3 '-di-t-butyl-5, 5 '-dimethoxydiphenyl (di-BHA) in rat tissues at different times (1-96 hr) following the intraperitoneal administration of a single dose of BHA (32 mg kg-' body weight) were monitored by gas
Distribution of a single oral dose of methyl mercury (10 mg Hg/kg body weight) was followed from 90 min up to 120 h in plasma, erythrocytes, and brain of Japanese quails and rats. Significantly higher Hg concentrations were observed in plasma and brain of quails and red blood cells of rats. Blood/br
The effect of a single oral dose of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), 10 microgram . kg-1, on the status of vitamin A (retinol) was studied in rats during an eight week period after administration. Retinol was determined spectrophotometrically after separation by means of high pressure liq