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Blocking of PI3K/AKT induces apoptosis by its effect on NF-κB activity in gastric carcinoma cell line SGC7901

✍ Scribed by Xu Chao; Jiang Zao; Gu Xiao-Yi; Meng Li-Jun; Shi Tao

Book ID: 116314322
Publisher: Elsevier Science
Year: 2010
Tongue: English
Weight: 316 KB
Volume: 64
Category: Article
ISSN: 0753-3322
DOI: 10.1016/j.biopha.2010.08.008

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## Abstract We previously reported that expression of angiogenesis factors interleukin‐8 (IL‐8) and vascular endothelial growth factor (VEGF) is promoted by coactivation of transcription factors nuclear factor‐kappaB (NF‐κB) and activator protein‐1 (AP‐1) by interleukin‐1α in human head and neck sq