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Blocking induction of T helper type 2 responses prevents development of disease in a model of childhood asthma

✍ Scribed by J. S. Siegle; N. Hansbro; C. Dong; P. Angkasekwinai; P. S. Foster; R. K. Kumar


Book ID
108701411
Publisher
John Wiley and Sons
Year
2011
Tongue
English
Weight
494 KB
Volume
165
Category
Article
ISSN
0009-9104

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The phosphodiesterase inhibitor pentoxifylline (POX), which is known to have pharmacological effects in animal models of multiorgan failure and endotoxinmediated shock, was tested for its immunosuppressive potential onT lymphocyte activation in vitro and in vivo. POX was found to have a profound inh