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Blockade of p38 mitogen-activated protein kinase pathway inhibits inducible nitric oxide synthase and gastric mucosal inflammatory reaction toHelicobacter pylorilipopolysaccharide

✍ Scribed by B. L. Slomiany; A. Slomiany

Book ID
111759244
Publisher
Springer
Year
2000
Tongue
English
Weight
179 KB
Volume
8
Category
Article
ISSN
0925-4692

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## Abstract Cytokine‐induced expression of inducible nitric oxide synthase (iNOS) and concomitant production of nitric oxide (NO) involve activation of mitogen‐activated protein (MAP) kinases and are in most cases mediated by the transcription factor NF‐κB. We investigated the role of p38 MAP kinas