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Blockade of B7-H1 enhances dendritic cell-mediated T cell response and antiviral immunity in HBV transgenic mice

✍ Scribed by Wenzheng Jiang

Book ID: 116964540
Publisher: Elsevier Science
Year: 2012
Tongue: English
Weight: 809 KB
Volume: 30
Category: Article
ISSN: 0264-410X
DOI: 10.1016/j.vaccine.2011.11.076

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## Abstract Tumor cells express tumor‐associated antigens (TAAs), which can serve as targets for the immune system. However, the majority of TAAs are overexpressed products of normal cellular genes; as such, self‐tolerance mechanisms have hindered their use for the induction of effective antitumor