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Blepharo-cheilo-dontic (BCD) syndrome in two Mexican patients

✍ Scribed by Vald�z-de la Torre, Ma. Hortensia; Quintana-Garc�a, M�nica; Can�n, Sonia

Publisher: John Wiley and Sons
Year: 1999
Tongue: English
Weight: 13 KB
Volume: 85
Category: Article
ISSN: 0148-7299
DOI: 10.1002/(sici)1096-8628(19990716)85:2<157::aid-ajmg10>3.0.co;2-a

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✦ Synopsis

The combination of lagophthalmia, ectropion of the lower eyelids, distichiasis, euryblepharon, cleft lip/palate, and oligodontia was recently named blepharo-cheilo-dontic (BCD) syndrome. Different combinations of these signs have been found sporadically, with autosomal dominant inheritance. Ectropion of the lower eyelids, lagophthalmia, and bilateral cleft lip/palate appear to be the more common manifestations. We report on two unrelated patients with bilateral cleft lip/palate and lagophthalmia. One of these two patients had familial cleft lip/ palate in two generations, probably as a variable expression of an autosomal dominant gene. Am.

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