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Bladder Cancer Predisposition: A Multigenic Approach to DNA-Repair and Cell-Cycle–Control Genes

✍ Scribed by Xifeng Wu; Jian Gu; H. Barton Grossman; Christopher I. Amos; Carol Etzel; Maosheng Huang; Qing Zhang; Randal E. Millikan; Seth Lerner; Colin P. Dinney; Margaret R. Spitz


Book ID
117854768
Publisher
American Society of Human Genetics
Year
2006
Tongue
English
Weight
314 KB
Volume
78
Category
Article
ISSN
0002-9297

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Individuals differ widely in their ability to repair DNA damage, and DNA-repair deficiency may be involved in modulating cancer risk. In a case-control study of 124 bladder-cancer patients and 85 hospital controls (urological and non-urological), 3 DNA polymorphisms localized in 3 genes of different