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Genetic variability in DNA repair and cell cycle control pathway genes and risk of smoking-related lung cancer

✍ Scribed by Shama C. Buch; Brenda Diergaarde; Tomoko Nukui; Roger S. Day; Jill M. Siegfried; Marjorie Romkes; Joel L. Weissfeld


Book ID
112142327
Publisher
John Wiley and Sons
Year
2011
Tongue
English
Weight
107 KB
Volume
51
Category
Article
ISSN
0899-1987

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## Abstract Tobacco‐related carcinogens cause a variety of DNA damage that is repaired by different enzymatic pathways, suggesting that DNA repair plays an important role in tobacco‐induced carcinogenesis. In a large hospital‐based case‐control study, we investigated DNA repair capacity (DRC) as a