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Bisphosphonate-related osteonecrosis of the skull base

✍ Scribed by Aayesha M. Khan; Raj Sindwani

Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
140 KB
Volume
119
Category
Article
ISSN
0023-852X

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✦ Synopsis

Abstract

Bisphosphonate‐related osteonecrosis of the jaw (BRONJ) is reported in up to 18.6% of patients treated with intravenous bisphosphonates and can result in significant morbidity. Most cases are managed by oral surgeons with only a handful of reports appearing in the otolaryngology literature. We present a unique case of extensive BRONJ involving the maxilla, sinuses, and skull base, complicated by sinusitis and an intracranial abscess. This is the first description of BRONJ involving the skull base. The pathogenesis and management of this process are reviewed. Laryngoscope, 119:449–452, 2009

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