The WT1 gene encodes a transcriptional regulator which during embryogenesis is involved in growth control and differentiation of diverse tissues. It is also expressed in few human malignancies, including acute leukemia. We tested 3 different monoclonal antibodies (MAbs H2, H7, HC17) and the polyvale
Biotyping of pathogenic fungi by the killer system and with monoclonal antibodies
โ Scribed by L. Polonelli; S. Conti; W. Magliani; G. Horace
- Publisher
- Springer Netherlands
- Year
- 1989
- Tongue
- English
- Weight
- 520 KB
- Volume
- 107
- Category
- Article
- ISSN
- 0301-486X
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โฆ Synopsis
Biotyping of pathogenic yeasts and hyphomycetes based on their suceptibility to selected killer yeasts and their reactivity with monoclonal antibodies are described. Both methods were used to differentiate fungi isolated from patients providing valuable epidemiological information on mycotic infections. The functional biotyping obtained with the two systems and the conventional auxenographic biocoding approaches commercially available for opportunistic yeasts are comparatively evaluated. The potential for biotyping of industrial fungal isolates is also discussed.
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