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Biotransformation of β-amino nitriles: the role of the N-protecting group

✍ Scribed by Margit Preiml; Helmut Hönig; Norbert Klempier

Book ID
113803720
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
94 KB
Volume
29
Category
Article
ISSN
1381-1177

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A new approach to β-amino acids: biotran
A new approach to β-amino acids: biotransformation of N-protected β-amino nitriles
✍ Margit Preiml; Kerstin Hillmayer; Norbert Klempier 📂 Article 📅 2003 🏛 Elsevier Science 🌐 French ⚖ 79 KB

A number of novel N-protected b-amino nitriles were prepared as substrates for two nitrile-converting microorganisms, Rhodococcus sp. R312 and Rhodococcus erythropolis NCIMB 11540. The respective biotransformation products, b-amino acids, are known to be pharmacological very potent compounds.