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Biotransformation of (−)-(R)-α-Phellandrene: Antimicrobial Activity of Its Major Metabolite

✍ Scribed by Gökalp İşcan; Neşe Kırımer; Fatih Demirci; Betül Demirci; Yoshiaki Noma; K. Hüsnü Can Başer

Book ID
115551260
Publisher
John Wiley and Sons
Year
2012
Tongue
English
Weight
173 KB
Volume
9
Category
Article
ISSN
1612-1872

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A convenient and chromatography-free synthesis for the enantiomers of fluoxetine and norfluoxetine is described. The synthesis relied on the use of the CBS reduction, and Hofman rearrangement to establish the key common intermediate 5, and enrichment of optical purity of the final product by crystal