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Biotransformation of methyltert-butyl ether by human cytochrome P450 2A6

✍ Scribed by Mojtaba Shamsipur; Ali Akbar Miran Beigi; Mohammad Teymouri; Tahereh Poursaberi; S. Mojtaba Mostafavi; Parviz Soleimani; Fereshteh Chitsazian; Shahram Abolhassan Tash

Book ID
113061969
Publisher
Springer Netherlands
Year
2011
Tongue
English
Weight
362 KB
Volume
23
Category
Article
ISSN
0923-9820

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## Objectives: The biotransformation of caffeine has been studied in vitro using human cytochrome p-450 isoenzymes (cyps) expressed in human b-lymphoblastoid cell lines, namely cyp1a1, 1a2, 2a6, 2b6, 2d6-val, 2e1 and 3a4, and microsomal epoxide hydroxylase (eh). in addition, cyp2d6-met was also stu