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Role of cytochromes P450 in the metabolism of methyl tert -butyl ether in human livers

✍ Scribed by Jun-Yan Hong; Chung S. Yang; Maojung Lee; Yong-Yu Wang; Wei-qun Huang; Yizheng Tan; Christopher J. Patten; Flordeliza Y. Bondoc


Publisher
Springer-Verlag
Year
1997
Tongue
English
Weight
100 KB
Volume
71
Category
Article
ISSN
0340-5761

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## Abstract Metabolites of the human carcinogen 4‐aminobiphenyl (4‐ABP) form hemoglobin (Hb) adducts, which represent a useful biomarker for exposure. However, not every individual responds to a similar degree to 4‐ABP exposure, and variations in 4‐ABP‐Hb adduct formation might be explained by gene