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Biotransformation of cholesterol to 1,4-androstadiene-3,17-dione (ADD) byNocardiaspecies

✍ Scribed by Preeti Sharma, Parvez S. Slathia, Priti Somal, Pardeep Mehta


Book ID
118302421
Publisher
Springer-Verlag
Year
2012
Tongue
English
Weight
269 KB
Volume
62
Category
Article
ISSN
1590-4261

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## Abstract A biotransformation process using __Mycobacterium__ sp was studied for androsta‐1, 4‐diene‐3,17‐dione (ADD) and androsta‐4‐ene‐3,17‐dione (AD) production from cholesterol. Cholesterol has a poor solubility in water (∼1.8 mg dm^βˆ’3^ at 25 °C), which makes it difficult to use as the substr