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Efficient biotransformation of cholesterol to androsta-1,4-diene-3,17-dione by a newly isolated actinomyceteGordonia neofelifaecis

✍ Scribed by Yuchang Liu; Guiying Chen; Fanglan Ge; Wei Li; Lihua Zeng; Weiguo Cao

Publisher
Springer
Year
2010
Tongue
English
Weight
307 KB
Volume
27
Category
Article
ISSN
1573-0972

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Lecithin-enhanced biotransformation of cholesterol to androsta-1,4-diene-3,17-dione and androsta-4-ene-3,17-dione
✍ Zhi Feng Wang; Yu Liang Huang; James F Rathman; Shang-Tian Yang 📂 Article 📅 2002 🏛 Wiley (John Wiley & Sons) 🌐 English ⚖ 158 KB

## Abstract A biotransformation process using __Mycobacterium__ sp was studied for androsta‐1, 4‐diene‐3,17‐dione (ADD) and androsta‐4‐ene‐3,17‐dione (AD) production from cholesterol. Cholesterol has a poor solubility in water (∼1.8 mg dm^−3^ at 25 °C), which makes it difficult to use as the substr