Biosynthetic origin of the carbon skeleton and oxygen atoms of the avermectins
β Scribed by Cane, David E.; Liang, Tzyy Chyau; Kaplan, Louis; Nallin, Mary K.; Schulman, Marvin D.; Hensens, Otto D.; Douglas, Alan W.; Albers-Schoenberg, Georg
- Book ID
- 126057816
- Publisher
- American Chemical Society
- Year
- 1983
- Tongue
- English
- Weight
- 363 KB
- Volume
- 105
- Category
- Article
- ISSN
- 0002-7863
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\({ }^{13}\)-labeling experiments were performed to determine the simple precursor metabolites that contribute to the tetrapyrrole skeleton of heme \(\mathrm{d}_{1}\). By use of \(5-\left[4^{-13} \mathrm{C}\right]\) aminolevulinic acid it was determined that the skeleton is derived from \(8 \mathrm{