Biosynthesis of trichothecin and related
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Y. Machida; S. Nozoe
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Article
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1972
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Elsevier Science
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French
β 364 KB
AImtract.--Tricbothecolone biosynthesized in the presence of doubly labeled mevalonate, [4(R)+'H,Z-'\*C]MVA, was degraded to show that the carbon atom at position 8 originated from C,,, of mevalonic acid. Two minor cytotoxic metabolites were isolated from 7Ikhothecium roseum and their biogenetic rel