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Biosynthesis of the triterpenoids, botryococcenes and tetramethylsqualene in the B race of Botryococcus braunii via the non-mevalonate pathway

✍ Scribed by Yohei Sato; Yusai Ito; Shigeru Okada; Masahiro Murakami; Hiroki Abe


Publisher
Elsevier Science
Year
2003
Tongue
French
Weight
127 KB
Volume
44
Category
Article
ISSN
0040-4039

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## Abstract In this paper, we describe the structure‐based design, synthesis, and biological evaluation of cytosine derivatives and analogues that inhibit IspF, an enzyme in the non‐mevalonate pathway of isoprenoid biosynthesis. This pathway is responsible for the biosynthesis of the C~5~ precursor