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Biosynthesis of RNA polymerase in Escherichia coli: V. Defects of the subunit assembly in a temperature-sensitive β subunit mutant

✍ Scribed by Makoto Taketo; Akira Ishihama

Book ID
119443541
Publisher
Elsevier Science
Year
1977
Tongue
English
Weight
746 KB
Volume
112
Category
Article
ISSN
0022-2836

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✍ Larionov, O. A. ;Gragerov, A. I. ;Kalyaeva, E. S. ;Nikiforov, V. G. 📂 Article 📅 1979 🏛 Springer 🌐 English ⚖ 603 KB

A cold-sensitive mutation in the rpoB gene for the RNA polymerase beta subunit increasing the temperature of promoter opening on T2 phage DNA was obtained in Escherichia coli. The mutation also affects the stages preceding promoter opening by increasing the dissociation rate of RNA polymerase--DNA c