Biosynthesis of citreothiolactone, citreopyrone and pyrenocine B
โ Scribed by Yoshikazu Shizuri; Seiji Kosemura; Shosuke Yamamura; Hideyuki Furukawa; Kazuaki Kawai; Nobuo Okada
- Publisher
- Elsevier Science
- Year
- 1984
- Tongue
- French
- Weight
- 105 KB
- Volume
- 25
- Category
- Article
- ISSN
- 0040-4039
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
Piericidins A(PA) and B(PB) are natural insecticidal substances isolated from mycellia of Streptomgces mobaraensis (l), and their structures have been elucidated as Ia and Ib, respectively (2,3). The novel structures prompted us to investigate the biosynthesis of these compounds using 14 C-labelled
The elucidation of the structures of the cochliobolins A J, and B 2 has recently been reported 1,2 . Inspection suggests that these substances are constructed from five isoprene units linked together head to tail, as shown in 2 for cochliobolin A.
Data are presented which shows that the llpoxlns are formed via a tetraene epoxlde. supportlng the asslgnment of the all trans tetraene geometry to llpoxin B.
## Abstract Sodium [2โ^13^C,2โ^2^H~3~]acetate was incorporated into cytochalasin B(**1**) by __Phoma exigua__ and into cytochalasin D (**2**) by __Zygosporium masonii__. The ^13^CโNMR. and ^2^HโNMR. of the metabolites showed that most of the deuterium was lost except at carbon atoms which are in po