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Biosynthesis of [1-15N]l-tryptophan from15N labeled anthranilic acid by fermentation ofCandida utilismutant

โœ Scribed by Zhanfeng Liu; Qipeng Yuan; Wenchuan Wang


Book ID
106221591
Publisher
Springer
Year
2008
Tongue
English
Weight
167 KB
Volume
36
Category
Article
ISSN
0939-4451

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## Abstract We have developed a stereospecific chemomicrobiological synthesis of labeled tryptophan. Lโ€[3โ€^13^C]Serine, [1โ€^15^N]โ€ and [2โ€^13^C]indole were used as precursors for the synthesis of Lโ€[ฮฒโ€^13^C]โ€, Lโ€[1โ€ฒโ€^15^N]โ€, and Lโ€[2โ€ฒโ€^13^C]tryptophan, respectively. The labeled precursors were inco