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Biosynthesis and processing of endogenous parathyroid hormone related peptide (PTHRP) by rat Leydig cell tumor H-500

✍ Scribed by Rabbani, Shafaat A.; Haq, Mahmudul; Goltzman, David

Book ID
126938665
Publisher
American Chemical Society
Year
1993
Tongue
English
Weight
760 KB
Volume
32
Category
Article
ISSN
0006-2960

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Inhibition of processing of parathyroid hormone-related peptide by anti-sense furin: Effect in vitro and in vivo on rat leydig (H-500) tumor cells
✍ Bin Liu; Norio Amizuka; David Goltzman; Shafaat A. Rabbani 📂 Article 📅 1995 🏛 John Wiley and Sons 🌐 French ⚖ 831 KB

## Abstract To attain full biological activity, the precursor pro‐parathyroid hormone‐related peptide (ProPTHRP) must be converted to the mature peptide PTHRP. We have examined the effect of inhibiting expression of the pro‐hormone convertase furin in H‐500 rat Leydig tumor cells on PTHRP productio