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Biophysical mechanisms of phospholipase A2 activation and their use in liposome-based drug delivery

✍ Scribed by Kent Jørgensen; Jesper Davidsen; Ole G Mouritsen


Book ID
117104714
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
315 KB
Volume
531
Category
Article
ISSN
0014-5793

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Secretory phospholipase A 2 (sPLA 2 ) belongs to a family of small interfacially active enzymes that catalyze the hydrolysis of phospholipids, yielding lysolipids and fatty acids. sPLA 2 is found in snake and bee venom and also in inflammatory and cancerous tissue. It is mainly active on organized l