Bioorganic chemistry: sterols and acrylic terpene terminal expoxides

Preparative bioorganic chemistry, XV. Pr

Preparative bioorganic chemistry, XV. Preparation of optically pure 2,4,4-trimethyl-2-cyclohexen-1-ol, a new and versatile chiral building block in terpene synthesis

✍ Mori, Kenji ;Puapoomchareon, Prapai 📂 Article 📅 1991 🏛 John Wiley and Sons 🌐 English ⚖ 476 KB

## Abstract Enzymatic hydrolysis of (±)‐2,4,4‐trimethyl‐2‐cyclohexenyl acetate [(±)‐3] with pig liver esterase yielded (__R__)‐(+)‐2,4,4‐trimethyl‐2‐cyclohexen‐1‐ol [(__R__)‐2] and unchanged (__S__)‐(−)‐acetate (__S__)‐3. Enantiomerically pure (__S__)‐2 was converted into (__R__)‐dihydro‐α‐ionone (