The intramolecular coupling reactions at the C-1 position of the 10Z-farnesyl moiety appended at the 2'-position of 4'-methoxy phenol derivatives were examined with the aid of Hf(OTf)4 and LiC104. When the phenol was protected with a TBDMS group, meta coupling predominated while para coupling occurr
Biomimetic Synthesis of (−)-Longithorone A
✍ Scribed by Layton, Mark E.; Morales, Carl A.; Shair, Matthew D.
- Book ID
- 120503725
- Publisher
- American Chemical Society
- Year
- 2002
- Tongue
- English
- Weight
- 57 KB
- Volume
- 124
- Category
- Article
- ISSN
- 0002-7863
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📜 SIMILAR VOLUMES
A bioqenetically patterned conversion of 1 into 2 is described. This transformation has been found to be non-stereospecific with respect to the geometry of the newly qenerated double bond at C-9(10). Leukotriene A (LTA), S(S)-trans-5,6-oxido-7,9-E-11,14-Z-eicosatetraenoic acid1 was shown to he an un
N-(Trifluoroacetyl)dehydrodipeptides 2-3 were coupled to aminomethylene dimethylacetal derivatives 4-5. The resulting pseudo-tripeptides 6 were stepwise deprotected (carbonyl function (7) then amine function) and in situ cyclized into imidazolopyrazines 1.