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Biomimetic Synthesis of (.+-.)-Galanthamine and Asymmetric Synthesis of (-)-Galanthamine Using Remote Asymmetric Induction.

โœ Scribed by Manabu Node; Sumiaki Kodama; Yoshio Hamashima; Takahiro Katoh; Kiyoharu Nishide; Tetsuya Kajimoto


Publisher
John Wiley and Sons
Year
2007
Weight
28 KB
Volume
38
Category
Article
ISSN
0931-7597

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## Abstract ^3^โ€(โ€“)โ€galanthamine (0.881 TBq/mmol) was synthesized via stereoselective reduction of (โ€“)โ€narwedine with tritiated Lโ€Selectride^ยฎ^. This reaction sequence was favored over an exchange of aromatic bromine with lithium aluminium tritide. Copyright ยฉ 2001 John Wiley & Sons Ltd.