Biomarkers to predict response to sunitinib therapy and prognosis in metastatic renal cell cancer
β Scribed by Takeshi Yuasa; Shunji Takahashi; Kiyohiko Hatake; Junji Yonese; Iwao Fukui
- Book ID
- 108589148
- Publisher
- John Wiley and Sons
- Year
- 2011
- Tongue
- English
- Weight
- 500 KB
- Volume
- 102
- Category
- Article
- ISSN
- 1347-9032
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## Abstract ## BACKGROUND Cyclooxygenaseβ2 (COXβ2) plays a major role in the development of cancer through numerous mechanisms. COXβ2 is expressed in the majority of renal cell carcinoma (RCC) tumors and correlates with stage, grade, and microvessel density. Based on potential additive or synergis