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Biomarkers in aerodigestive tract chemoprevention trials

โœ Scribed by Lee, Jin S.; Lippman, Scott M.; Hong, Waun K.; Ro, Jae Y.; Lotan, Reuben; Hittelman, Walter N.

Book ID
122598896
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
638 KB
Volume
9
Category
Article
ISSN
0169-5002

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Intermediate biomarkers in upper aerodig
Intermediate biomarkers in upper aerodigestive tract and lung chemoprevention trials
โœ Steven E. Benner; Waun K. Hong; Scott M. Lippman; Jin S. Lee; Walter M. Hittelma ๐Ÿ“‚ Article ๐Ÿ“… 1992 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 510 KB

Chemoprevention trials in lung and upper aerodigestive tract (UADT) cancer are guided by the field cancerization hypothesis. Inhaled carcinogens place the entire epithelial lining at risk for the development of cancer. The hypothesis is supported by the occurrence of premalignant lesions, such as le